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Normal expression of DNA repair proteins, hMre11, Rad50 and Rad51 but protracted formation of Rad50 containing foci in X-irradiated skin fibroblasts from radiosensitive cancer patients

About 5% of oncology patients treated by radiation therapy develop acute or late radiotoxic effects whose molecular mechanisms remain poorly understood. In this study, we evaluated the potential role of DNA repair proteins in the hypersensitivity of cancer patients to radiation therapy. The expressi...

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Detalles Bibliográficos
Autores principales: Djuzenova, C, Mühl, B, Schakowski, R, Oppitz, U, Flentje, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409526/
https://www.ncbi.nlm.nih.gov/pubmed/15150571
http://dx.doi.org/10.1038/sj.bjc.6601878