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Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling

In normal human kidney, NOS1 and soluble guanylate cyclase (sGC) are expressed in tubular epithelial cells, suggesting a physiological autocrine NO signalling pathway. Therefore, we investigated both NOS1 and sGC expressions in benign and malignant renal tumours. In addition, we examined the pattern...

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Detalles Bibliográficos
Autores principales: Renaudin, K, Denis, M G, Karam, G, Vallette, G, Buzelin, F, Laboisse, C L, Jarry, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409527/
https://www.ncbi.nlm.nih.gov/pubmed/15150612
http://dx.doi.org/10.1038/sj.bjc.6601809