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Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling
In normal human kidney, NOS1 and soluble guanylate cyclase (sGC) are expressed in tubular epithelial cells, suggesting a physiological autocrine NO signalling pathway. Therefore, we investigated both NOS1 and sGC expressions in benign and malignant renal tumours. In addition, we examined the pattern...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409527/ https://www.ncbi.nlm.nih.gov/pubmed/15150612 http://dx.doi.org/10.1038/sj.bjc.6601809 |