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Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers

The fragile histidine triad (FHIT) gene, encompassing the FRA3B fragile site at chromosome 3p14.2, is a tumour suppressor gene involved in different tumour types including non-small-cell lung cancers (NSCLCs). In the current study, we examined for allelic deletion at the FHIT locus in 58 primary and...

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Detalles Bibliográficos
Autores principales: Lee, Y-C, Wu, C-T, Shih, J-Y, Jou, Y-S, Chang, Y-L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409530/
https://www.ncbi.nlm.nih.gov/pubmed/15150628
http://dx.doi.org/10.1038/sj.bjc.6601778