Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation

The aim of this study was to find factors that could explain the accumulation difference of mitoxantrone in the BCRP1-negative GLC4-MITO cell line compared to GLC4. Comparative genomic hybridisation (CGH) was applied to determine chromosomal differences between GLC4 and GLC4-MITO. Comparative genomi...

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Detalles Bibliográficos
Autores principales: Boonstra, R, Timmer-Bosscha, H, van Echten-Arends, J, van der Kolk, D M, van den Berg, A, de Jong, B, Tew, K D, Poppema, S, de Vries, E G E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409533/
https://www.ncbi.nlm.nih.gov/pubmed/15150577
http://dx.doi.org/10.1038/sj.bjc.6601863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409533/
https://www.ncbi.nlm.nih.gov/pubmed/15150577
http://dx.doi.org/10.1038/sj.bjc.6601863

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