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Antiangiogenic activity of aplidine, a new agent of marine origin

The antineoplastic compound aplidine, a new marine-derived depsipeptide, has shown preclinical activity in vitro on haematological and solid tumour cell lines. It is currently in early phase clinical trials. The exact mechanism of action of this anticancer agent still needs to be clarified. We have...

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Detalles Bibliográficos
Autores principales: Taraboletti, G, Poli, M, Dossi, R, Manenti, L, Borsotti, P, Faircloth, G T, Broggini, M, D'Incalci, M, Ribatti, D, Giavazzi, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409535/
https://www.ncbi.nlm.nih.gov/pubmed/15173857
http://dx.doi.org/10.1038/sj.bjc.6601864