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Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase

TIMP-1, an ∼30 kDa glycosylated protein found predominantly in extracellular compartments, is involved in the regulation of a variety of developmental, remodelling, and pathological processes. One function of TIMP-1 is to inhibit certain members of a group of extracellular and cell surface enzymes k...

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Detalles Bibliográficos
Autores principales: Porter, J F, Shen, S, Denhardt, D T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409564/
https://www.ncbi.nlm.nih.gov/pubmed/14735194
http://dx.doi.org/10.1038/sj.bjc.6601533