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Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been reported to reduce the risk and mortality of colorectal cancer (CRC) by inhibiting the activity of cyclooxygenase (COX). The present studies were directed to determine whether selective COX-2 inhibition reduces CRC tumour cell proliferation and...

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Detalles Bibliográficos
Autores principales: Yao, M, Lam, E C, Kelly, C R, Zhou, W, Wolfe, M M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409599/
https://www.ncbi.nlm.nih.gov/pubmed/14760389
http://dx.doi.org/10.1038/sj.bjc.6601489