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CDH13 promoter region is specifically methylated in poorly differentiated colorectal cancer

It has recently become clear that CDH13 (H-cadherin, T-cadherin) expression is frequently silenced by aberrant methylation in colorectal cancers and adenomas. In this study, we investigated the methylation status of CDH13 gene and detected aberrant promoter methylation in 27 of 84 (32%) colorectal c...

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Detalles Bibliográficos
Autores principales: Hibi, K, Nakayama, H, Kodera, Y, Ito, K, Akiyama, S, Nakao, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409627/
https://www.ncbi.nlm.nih.gov/pubmed/14997203
http://dx.doi.org/10.1038/sj.bjc.6601647