Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells

Malignant gliomas highly coexpress platelet-derived growth factor (PDGF) and its receptor, suggesting the presence of an autocrine loop. Therefore, disruption of PDGF ligand/receptor complex represents a promising strategy for the treatment of malignant gliomas. However, the mechanisms of the antitu...

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Detalles Bibliográficos
Autores principales: Takeuchi, H, Kanzawa, T, Kondo, Y, Kondo, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409632/
https://www.ncbi.nlm.nih.gov/pubmed/14997209
http://dx.doi.org/10.1038/sj.bjc.6601605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409632/
https://www.ncbi.nlm.nih.gov/pubmed/14997209
http://dx.doi.org/10.1038/sj.bjc.6601605

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