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Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells
Malignant gliomas highly coexpress platelet-derived growth factor (PDGF) and its receptor, suggesting the presence of an autocrine loop. Therefore, disruption of PDGF ligand/receptor complex represents a promising strategy for the treatment of malignant gliomas. However, the mechanisms of the antitu...
Autores principales: | Takeuchi, H, Kanzawa, T, Kondo, Y, Kondo, S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409632/ https://www.ncbi.nlm.nih.gov/pubmed/14997209 http://dx.doi.org/10.1038/sj.bjc.6601605 |
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