Specific roles for the PI3K and the MEK–ERK pathway in IGF-1-stimulated chemotaxis, VEGF secretion and proliferation of multiple myeloma cells: study in the 5T33MM model

Insulin-like growth factor-1 (IGF-1) has been described as an important factor in proliferation, cell survival and migration of multiple myeloma (MM) cells. Angiogenesis correlates with development and prognosis of the MM disease. Vascular endothelial growth factor (VEGF) is one of the prominent fac...

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Detalles Bibliográficos
Autores principales: Menu, E, Kooijman, R, Valckenborgh, E Van, Asosingh, K, Bakkus, M, Camp, B Van, Vanderkerken, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409634/
https://www.ncbi.nlm.nih.gov/pubmed/14997210
http://dx.doi.org/10.1038/sj.bjc.6601613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409634/
https://www.ncbi.nlm.nih.gov/pubmed/14997210
http://dx.doi.org/10.1038/sj.bjc.6601613

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