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BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families
Worldwide variation in the distribution of BRCA1 and BRCA2 mutations is well recognised, and for the Belgian population no comprehensive studies about BRCA1/2 mutation spectra or frequencies have been published. We screened the complete coding region of both genes in 451 individuals from 349 Belgian...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409651/ https://www.ncbi.nlm.nih.gov/pubmed/15026808 http://dx.doi.org/10.1038/sj.bjc.6601656 |