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BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families

Worldwide variation in the distribution of BRCA1 and BRCA2 mutations is well recognised, and for the Belgian population no comprehensive studies about BRCA1/2 mutation spectra or frequencies have been published. We screened the complete coding region of both genes in 451 individuals from 349 Belgian...

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Detalles Bibliográficos
Autores principales:	Claes, K, Poppe, B, Coene, I, Paepe, A De, Messiaen, L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409651/ https://www.ncbi.nlm.nih.gov/pubmed/15026808 http://dx.doi.org/10.1038/sj.bjc.6601656

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