Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells

Loss of E-cadherin (E-cad) triggers invasion, metastasis, and dedifferentiation in various epithelial carcinomas. Recently, it has been reported that two transcription factors, Snail and SIP1 (Smad interacting protein 1), directly repress transcription of the E-cad gene by binding E-box on E-cad pro...

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Detalles Bibliográficos
Autores principales: Miyoshi, A, Kitajima, Y, Sumi, K, Sato, K, Hagiwara, A, Koga, Y, Miyazaki, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409652/
https://www.ncbi.nlm.nih.gov/pubmed/15026811
http://dx.doi.org/10.1038/sj.bjc.6601685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409652/
https://www.ncbi.nlm.nih.gov/pubmed/15026811
http://dx.doi.org/10.1038/sj.bjc.6601685

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