Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft

IDN 5390 is a novel C-seco taxane analogue selected for preclinical development on the basis of its antimotility activity on endothelial cells, antitumour efficacy in a large panel of human tumour xenografts and high tolerability in mouse. On the basis of oral availability, IDN 5390 is suitable for...

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Detalles Bibliográficos
Autores principales: Petrangolini, G, Cassinelli, G, Pratesi, G, Tortoreto, M, Favini, E, Supino, R, Lanzi, C, Belluco, S, Zunino, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409671/
https://www.ncbi.nlm.nih.gov/pubmed/15054472
http://dx.doi.org/10.1038/sj.bjc.6601730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409671/
https://www.ncbi.nlm.nih.gov/pubmed/15054472
http://dx.doi.org/10.1038/sj.bjc.6601730

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