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Osteopontin expression correlates with adhesive and metastatic potential in metastasis-inducing DNA-transfected rat mammary cell lines

A metastatic phenotype can be induced in benign rat mammary cells (Rama 37 cells) by transfecting them with metastasis-inducing DNAs (Met-DNAs). Stable transfection of Met-DNAs increases the level of the metastasis-associated protein, osteopontin. Randomly picked clonal cell lines have been establis...

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Detalles Bibliográficos
Autores principales: Moye, V E, Barraclough, R, West, C, Rudland, P S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409741/
https://www.ncbi.nlm.nih.gov/pubmed/15150606
http://dx.doi.org/10.1038/sj.bjc.6601683