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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells

The platinum compound oxaliplatin has been shown to be an effective chemotherapeutic agent for the treatment of colorectal cancer. In this study, we investigate the molecular mechanisms of action of oxaliplatin to identify means of predicting response to this agent. Exposure of colon cancer cells to...

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Detalles Bibliográficos
Autores principales: Arango, D, Wilson, A J, Shi, Q, Corner, G A, Arañes, M J, Nicholas, C, Lesser, M, Mariadason, J M, Augenlicht, L H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409767/
https://www.ncbi.nlm.nih.gov/pubmed/15545975
http://dx.doi.org/10.1038/sj.bjc.6602215