Coexistence of treatment-related MLL cleavage and rearrangement in a child with haemophagocytic lymphohistiocytosis

Treatment-related acute myeloid leukaemia (t-AML) is a serious complication of topoisomerase 2 inhibitor therapy and is characterised by the presence of mixed lineage leukaemia (MLL) rearrangement. By molecular tracking, we were able to show that MLL cleavage preceded gene rearrangement by 3 months...

Descripción completa

Detalles Bibliográficos
Autores principales: Ng, A, Ravetto, P F, Taylor, G M, Wynn, R F, Eden, O B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409780/
https://www.ncbi.nlm.nih.gov/pubmed/15570305
http://dx.doi.org/10.1038/sj.bjc.6602269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409780/
https://www.ncbi.nlm.nih.gov/pubmed/15570305
http://dx.doi.org/10.1038/sj.bjc.6602269

Ejemplares similares