Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome

Host genomic abnormalities may determine the natural history of cervical squamous intraepithelial lesions (SILs). We undertook comparative genomic hybridisation analysis of epithelium carefully microdissected from 70 cervical SILs, the largest series to date. In contrast to previous studies, we used...

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Detalles Bibliográficos
Autores principales: Alazawi, W, Pett, M, Strauss, S, Moseley, R, Gray, J, Stanley, M, Coleman, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409784/
https://www.ncbi.nlm.nih.gov/pubmed/15545968
http://dx.doi.org/10.1038/sj.bjc.6602237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409784/
https://www.ncbi.nlm.nih.gov/pubmed/15545968
http://dx.doi.org/10.1038/sj.bjc.6602237

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