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Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome
Host genomic abnormalities may determine the natural history of cervical squamous intraepithelial lesions (SILs). We undertook comparative genomic hybridisation analysis of epithelium carefully microdissected from 70 cervical SILs, the largest series to date. In contrast to previous studies, we used...
Autores principales: | Alazawi, W, Pett, M, Strauss, S, Moseley, R, Gray, J, Stanley, M, Coleman, N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409784/ https://www.ncbi.nlm.nih.gov/pubmed/15545968 http://dx.doi.org/10.1038/sj.bjc.6602237 |
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