Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma

KIT and PDGFRA are receptor tyrosine kinases that can be specifically inactivated by small-molecule tyrosine kinase inhibitors, notably imatinib mesylate. In ovarian carcinoma, expression of KIT and PDGFRA protein has been documented, but the frequency and the molecular background of expression are...

Descripción completa

Detalles Bibliográficos
Autores principales: Lassus, H, Sihto, H, Leminen, A, Nordling, S, Joensuu, H, Nupponen, N N, Butzow, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409787/
https://www.ncbi.nlm.nih.gov/pubmed/15583695
http://dx.doi.org/10.1038/sj.bjc.6602252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409787/
https://www.ncbi.nlm.nih.gov/pubmed/15583695
http://dx.doi.org/10.1038/sj.bjc.6602252

Ejemplares similares