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Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma

KIT and PDGFRA are receptor tyrosine kinases that can be specifically inactivated by small-molecule tyrosine kinase inhibitors, notably imatinib mesylate. In ovarian carcinoma, expression of KIT and PDGFRA protein has been documented, but the frequency and the molecular background of expression are...

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Detalles Bibliográficos
Autores principales:	Lassus, H, Sihto, H, Leminen, A, Nordling, S, Joensuu, H, Nupponen, N N, Butzow, R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409787/ https://www.ncbi.nlm.nih.gov/pubmed/15583695 http://dx.doi.org/10.1038/sj.bjc.6602252

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