Cargando…
Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells
Reduced accumulation of cisplatin is the most consistent feature seen in cisplatin-resistant (CP-r) cells that are cross-resistant to other cytotoxic compounds, such as methotrexate. In this report, defective uptake of a broad range of compounds, including [(14)C]-carboplatin, [(3)H]MTX, [(3)H]folic...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2004
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409801/ https://www.ncbi.nlm.nih.gov/pubmed/15199393 http://dx.doi.org/10.1038/sj.bjc.6601956 |