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A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer

In this marker evaluation study, we tested whether distinct patterns of functional genomic polymorphisms in genes involved in drug metabolic pathways and DNA repair that predict clinical outcome to 5-fluorouracil (5-FU)/oxaliplatin chemotherapy in patients with advanced colorectal cancer could be id...

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Detalles Bibliográficos
Autores principales: Stoehlmacher, J, Park, D J, Zhang, W, Yang, D, Groshen, S, Zahedy, S, Lenz, H-J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409815/
https://www.ncbi.nlm.nih.gov/pubmed/15213713
http://dx.doi.org/10.1038/sj.bjc.6601975