Telomere shortening and mitotic dysfunction generate cytogenetic heterogeneity in a subgroup of renal cell carcinomas

Most renal cell carcinomas (RCC) show only simple chromosomal changes. However, a more complex cytogenetic pattern has been found in a subgroup of aggressive RCC, indicating that further accumulation of chromosome changes could play a role in tumour progression. To explore the possible mechanisms be...

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Detalles Bibliográficos
Autores principales: Gisselsson, D, Gorunova, L, Höglund, M, Mandahl, N, Elfving, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409829/
https://www.ncbi.nlm.nih.gov/pubmed/15162157
http://dx.doi.org/10.1038/sj.bjc.6601803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409829/
https://www.ncbi.nlm.nih.gov/pubmed/15162157
http://dx.doi.org/10.1038/sj.bjc.6601803

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