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Targeting the epidermal growth factor receptor

The epidermal growth factor receptor (EGFR) is a member of the erbB family of tyrosine kinase receptors (RTK). The EGFR is involved in cell proliferation, metastasis and angiogenesis, and is expressed in a large proportion of epithelial tumours. The two main classes of EGFR inhibitors in clinical tr...

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Detalles Bibliográficos
Autores principales: El-Rayes, B F, LoRusso, P M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409851/
https://www.ncbi.nlm.nih.gov/pubmed/15238978
http://dx.doi.org/10.1038/sj.bjc.6601921