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Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin™
Aplidin™ (APL) is a new antitumoral drug from marine origin currently in phase II clinical trials against a wide multiplicity of cancers. As resistance may be, as with other drugs, an important obstacle to the APL therapeutic efficacy, we have established an acquired resistance cellular model by con...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409906/ https://www.ncbi.nlm.nih.gov/pubmed/15365569 http://dx.doi.org/10.1038/sj.bjc.6602166 |