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Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors

Local adenoviral gene transfer can be performed by means of isolated hepatic perfusion (IHP). This methodology is a very effective and safe way to deliver adenoviral vectors. We studied the immune response after IHP. A decreased neutralising antibody formation was observed, offering possibilities fo...

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Detalles Bibliográficos
Autores principales: van Etten, B, Eggermont, A M M, Ambagtsheer, G, van Tiel, S T, ten Hagen, T L M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409916/
https://www.ncbi.nlm.nih.gov/pubmed/15480435
http://dx.doi.org/10.1038/sj.bjc.6602151