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Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil

Building upon the concept of schedule-specific biochemical modulation of 5-fluorouracil (FU), which alternates bolus and continuous infusion (CI) FU, we have incorporated oxaliplatin (l-OHP) following the bolus part of the regimen to explore the activity of this new combination. Patients with advanc...

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Detalles Bibliográficos
Autores principales: Guglielmi, A, Barni, S, Zaniboni, A, Pella, N, Belvedere, O, Beretta, G D, Grossi, F, Frontini, L, Puglisi, F, Labianca, R, Sobrero, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409920/
https://www.ncbi.nlm.nih.gov/pubmed/15381935
http://dx.doi.org/10.1038/sj.bjc.6602176