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Characterisation of molecular events following cisplatin treatment of two curable ovarian cancer models: contrasting role for p53 induction and apoptosis in vivo

The detailed molecular basis and determinants of in vivo tumour sensitivity to conventional anticancer agents remain unclear. We examined the cellular and molecular consequences of cisplatin treatment using two ovarian tumour xenograft models that had not been previously adapted to culture in vitro....

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Detalles Bibliográficos
Autores principales: Clarke, P A, Pestell, K E, Di Stefano, F, Workman, P, Walton, M I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409921/
https://www.ncbi.nlm.nih.gov/pubmed/15452549
http://dx.doi.org/10.1038/sj.bjc.6602167