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Characterisation of molecular events following cisplatin treatment of two curable ovarian cancer models: contrasting role for p53 induction and apoptosis in vivo
The detailed molecular basis and determinants of in vivo tumour sensitivity to conventional anticancer agents remain unclear. We examined the cellular and molecular consequences of cisplatin treatment using two ovarian tumour xenograft models that had not been previously adapted to culture in vitro....
Autores principales: | Clarke, P A, Pestell, K E, Di Stefano, F, Workman, P, Walton, M I |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409921/ https://www.ncbi.nlm.nih.gov/pubmed/15452549 http://dx.doi.org/10.1038/sj.bjc.6602167 |
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