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The BOADICEA model of genetic susceptibility to breast and ovarian cancer

Several genes conferring susceptibility to breast and ovarian cancer, notably BRCA1 and BRCA2, have been identified. The majority of the familial aggregation of breast cancer is, however, not explained by these genes. We have previously derived, using segregation analysis, a susceptibility model (BO...

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Detalles Bibliográficos
Autores principales: Antoniou, A C, Pharoah, P P D, Smith, P, Easton, D F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409934/
https://www.ncbi.nlm.nih.gov/pubmed/15381934
http://dx.doi.org/10.1038/sj.bjc.6602175