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Lack of efficacy of troglitazone at clinically achievable concentrations, with or without 9-cis retinoic acid or cytotoxic agents, for hepatocellular carcinoma cell lines

Although the PPARγ agonist troglitazone has been shown to induce growth inhibition of hepatocellular carcinoma (HCC) cells at high concentration, this study indicates troglitazone does not significantly inhibit the growth of HCC cells at clinically achievable concentrations (1–10 μM), and this lack...

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Detalles Bibliográficos
Autores principales: Shen, Y-C, Hsu, C, Chen, J-Y, Cheng, A-L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409938/
https://www.ncbi.nlm.nih.gov/pubmed/15467764
http://dx.doi.org/10.1038/sj.bjc.6602200