Mutant, wild type, or overall p53 expression: freedom from clinical progression in tumours of astrocytic lineage

Abnormalities of the p53 tumor-suppressor gene are found in a significant proportion of astrocytic brain tumours. We studied tumour specimens from 74 patients evaluated over 20 years at the Massachusetts General Hospital, where clinical outcome could be determined and sufficient pathologic material...

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Detalles Bibliográficos
Autores principales: Pardo, F S, Hsu, D W, Zeheb, R, Efird, J T, Okunieff, P G, Malkin, D M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409947/
https://www.ncbi.nlm.nih.gov/pubmed/15494720
http://dx.doi.org/10.1038/sj.bjc.6602161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409947/
https://www.ncbi.nlm.nih.gov/pubmed/15494720
http://dx.doi.org/10.1038/sj.bjc.6602161

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