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Expression of FAP-1 by human colon adenocarcinoma: implication for resistance against Fas-mediated apoptosis in cancer

Although colon carcinoma cells express Fas receptors, they are resistant to Fas-mediated apoptosis. Defects within the intracellular Fas signal transduction may be responsible. We investigated whether the Fas-associated phosphatase-1 (FAP-1), an inhibitor of Fas signal transduction, contributed to t...

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Detalles Bibliográficos
Autores principales: Yao, H, Song, E, Chen, J, Hamar, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409949/
https://www.ncbi.nlm.nih.gov/pubmed/15494722
http://dx.doi.org/10.1038/sj.bjc.6602136