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Inverse relationship between ER-β and SRC-1 predicts outcome in endocrine-resistant breast cancer

The oestrogen receptor (ER) interacts with coactivator proteins to modulate genes central to breast tumour progression. Oestrogen receptor is encoded for by two genes, ER-α and ER-β. Although ER-α has been well characterized, the role of ER-β as a prognostic indicator remains unresolved. To determin...

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Detalles Bibliográficos
Autores principales: Myers, E, Fleming, F J, Crotty, T B, Kelly, G, McDermott, E W, O'Higgins, N J, Hill, A D K, Young, L S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409954/
https://www.ncbi.nlm.nih.gov/pubmed/15477868
http://dx.doi.org/10.1038/sj.bjc.6602156