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Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells

Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show that an organic extract of khat induces a selective type of cell death having a...

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Detalles Bibliográficos
Autores principales: Dimba, E A O, Gjertsen, B T, Bredholt, T, Fossan, K O, Costea, D E, Francis, G W, Johannessen, A C, Vintermyr, O K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409956/
https://www.ncbi.nlm.nih.gov/pubmed/15477863
http://dx.doi.org/10.1038/sj.bjc.6602197