Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer

Proliferating cells, especially tumour cells, express a special isoenzyme of pyruvate kinase, termed M2-PK, which can occur in a tetrameric form with a high affinity to its substrate, phosphoenolpyruvate (PEP), and in a dimeric form with a low PEP affinity. In tumour cells, the dimeric form is usual...

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Detalles Bibliográficos
Autores principales: Hardt, P D, Mazurek, S, Toepler, M, Schlierbach, P, Bretzel, R G, Eigenbrodt, E, Kloer, H U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409989/
https://www.ncbi.nlm.nih.gov/pubmed/15266315
http://dx.doi.org/10.1038/sj.bjc.6602033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409989/
https://www.ncbi.nlm.nih.gov/pubmed/15266315
http://dx.doi.org/10.1038/sj.bjc.6602033

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