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Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function
Oestrogen receptor alpha (ERα) is an oestrogen-activated transcription factor, which regulates proliferation and differentiation of mammary epithelial cells by activating or repressing gene expression. ERα is a critical prognostic indicator and a therapeutic target for breast cancer. Patients with t...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410160/ https://www.ncbi.nlm.nih.gov/pubmed/14970864 http://dx.doi.org/10.1038/sj.bjc.6601541 |