Cargando…
Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function
Oestrogen receptor alpha (ERα) is an oestrogen-activated transcription factor, which regulates proliferation and differentiation of mammary epithelial cells by activating or repressing gene expression. ERα is a critical prognostic indicator and a therapeutic target for breast cancer. Patients with t...
Autores principales: | Bhat-Nakshatri, P, Campbell, R A, Patel, N M, Newton, T R, King, A J, Marshall, M S, Ali, S, Nakshatri, H |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410160/ https://www.ncbi.nlm.nih.gov/pubmed/14970864 http://dx.doi.org/10.1038/sj.bjc.6601541 |
Ejemplares similares
-
The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancer
por: Kaas, R, et al.
Publicado: (2003) -
Biological response to hormonal manipulation in oestrogen receptor positive ductal carcinoma in situ of the breast
por: Boland, G P, et al.
Publicado: (2003) -
Expression of oestrogen receptor beta (ERβ1) protein in human breast cancer biopsies
por: Saunders, P T K, et al.
Publicado: (2002) -
Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells
por: Journe, F, et al.
Publicado: (2004) -
Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer
por: Murphy, L C, et al.
Publicado: (2002)