Cellular responses to ionising radiation of AT heterozygotes: differences between missense and truncating mutation carriers

It has been estimated that approximately 1% of the general population are ataxia telangiectasia (AT) mutated (ATM) heterozygotes. The ATM protein plays a central role in DNA-damage response pathways; however, the functional consequences of the presence of either heterozygous truncating or missense m...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernet, M, Moullan, N, Lauge, A, Stoppa-Lyonnet, D, Hall, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410162/
https://www.ncbi.nlm.nih.gov/pubmed/14970866
http://dx.doi.org/10.1038/sj.bjc.6601549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410162/
https://www.ncbi.nlm.nih.gov/pubmed/14970866
http://dx.doi.org/10.1038/sj.bjc.6601549

Ejemplares similares