Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth

Although heat-shock protein 70 (Hsp70) has been considered an intracellular protein, we report that Hsp70 is secreted under normal cell culture conditions by human prostate cell lines, LAPC-4, PC-3, CWR-22, RWPE-1 and -2, LNCaP, and TRAMP (transgenic adenocarcinoma mouse prostate)-C2. We found that...

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Detalles Bibliográficos
Autores principales: Wang, M-H, Grossmann, M E, Young, C Y F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410170/
https://www.ncbi.nlm.nih.gov/pubmed/14970875
http://dx.doi.org/10.1038/sj.bjc.6601583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410170/
https://www.ncbi.nlm.nih.gov/pubmed/14970875
http://dx.doi.org/10.1038/sj.bjc.6601583

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