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Demethylation of MAGE promoters during gastric cancer progression

Melanoma antigen (MAGE)-encoding genes are expressed in various tumour types via demethylation of their promoter CpG islands, which are silent in all non-neoplastic tissues except for the testis and placenta. The clinicopathological significance of demethylation of MAGE genes in gastric carcinoma is...

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Detalles Bibliográficos
Autores principales: Honda, T, Tamura, G, Waki, T, Kawata, S, Terashima, M, Nishizuka, S, Motoyama, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410179/
https://www.ncbi.nlm.nih.gov/pubmed/14970862
http://dx.doi.org/10.1038/sj.bjc.6601600