Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice

5,6-Dimethylxanthenone-4-acetic acid (DMXAA) is currently undergoing clinical evaluation as an antivascular agent for the treatment of cancer. We have previously demonstrated that DMXAA induces apoptosis of vascular endothelial cells in murine tumour sections and in a breast carcinoma biopsy from on...

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Detalles Bibliográficos
Autores principales: Ching, L-M, Zwain, S, Baguley, B C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410181/
https://www.ncbi.nlm.nih.gov/pubmed/14970872
http://dx.doi.org/10.1038/sj.bjc.6601606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410181/
https://www.ncbi.nlm.nih.gov/pubmed/14970872
http://dx.doi.org/10.1038/sj.bjc.6601606

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