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N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1

Apoptosis of hepatic stellate cells (HSC) has previously been shown to occur during spontaneous resolution of experimental liver fibrosis. TIMP-1 has also been shown to have a key role because of its ability to inhibit apoptosis of HSC via matrix metalloproteinase (MMP) inhibition. This has led to f...

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Detalles Bibliográficos
Autores principales: Murphy, Frank, Waung, Julian, Collins, Jane, Arthur, Michael JP, Nagase, Hideaki, Mann, Derek, Benyon, R Christopher, Iredale, John P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410231/
https://www.ncbi.nlm.nih.gov/pubmed/14960160
http://dx.doi.org/10.1186/1476-5926-2-S1-S8