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Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia

INTRODUCTION: Heme oxygenase-1 (HO-1) is a stress response enzyme, which catalyses the breakdown of heme into biliverdin-IX alpha, carbon monoxide and ferrous iron. Under situations of oxidative stress, heat stress, ischemia/reperfusion injury or endotoxemia, HO-1 has been shown to be induced and to...

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Detalles Bibliográficos
Autores principales: Dorman, Robert B, Bajt, Mary Lynn, Farhood, Anwar, Mayes, January, Jaeschke, Hartmut
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410259/
https://www.ncbi.nlm.nih.gov/pubmed/14960194
http://dx.doi.org/10.1186/1476-5926-2-S1-S42