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Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice

INTRODUCTION: Vascular injury and accumulation of red blood cells in the space of Disse (hemorrhage) is a characteristic feature of acetaminophen hepatotoxicity. However, the mechanism of nonparenchymal cell injury is unclear. Therefore, the objective was to investigate if either Kupffer cells or in...

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Detalles Bibliográficos
Autores principales: Knight, Tamara R, Jaeschke, Hartmut
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410261/
https://www.ncbi.nlm.nih.gov/pubmed/14960198
http://dx.doi.org/10.1186/1476-5926-2-S1-S46