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Epidermal growth factor receptor tyrosine kinase inhibitors

Activation of the epidermal growth factor receptor (EGFR) has been linked to tumour proliferation, invasion, metastasis and angiogenesis in epithelial tumours. Inhibitors of the EGFR have emerged as promising anticancer agents and two main approaches have been developed, humanised monoclonal antibod...

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Detalles Bibliográficos
Autor principal: Ranson, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410290/
https://www.ncbi.nlm.nih.gov/pubmed/15150574
http://dx.doi.org/10.1038/sj.bjc.6601873