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Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell culture

BACKGROUND: Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (U(L)) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACΔ58) from the Oka...

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Detalles Bibliográficos
Autores principales: Yoshii, Hironori, Sadaoka, Kay, Matsuura, Masaaki, Nagaike, Kazuhiro, Takahashi, Michiaki, Yamanishi, Koichi, Mori, Yasuko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2412858/
https://www.ncbi.nlm.nih.gov/pubmed/18445300
http://dx.doi.org/10.1186/1743-422X-5-54