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Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR

BACKGROUND: The rate of transcription of the HIV-1 viral genome is mediated by the interaction of the viral protein Tat with the LTR and other transcriptional machinery. These specific interactions can be affected by the state of post-translational modifications on Tat. Previously, we have shown tha...

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Detalles Bibliográficos
Autores principales: Van Duyne, Rachel, Easley, Rebecca, Wu, Weilin, Berro, Reem, Pedati, Caitlin, Klase, Zachary, Kehn-Hall, Kylene, Flynn, Elizabeth K, Symer, David E, Kashanchi, Fatah
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2412914/
https://www.ncbi.nlm.nih.gov/pubmed/18498648
http://dx.doi.org/10.1186/1742-4690-5-40